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Support is the most important aspect of purchasing plus size bras. Without proper breast support, you could experience sagging (caused by stretching Cooper's ligaments) and a strain on your neck and upper back. Breasts should sit firmly in the middle of your chest and a bra should prevent movement. Underwire bras are usually recommended for optimal support; but a properly fitted wire-free style can be just as effective.
To ensure you have the right fit, make sure your nipple sits directly in the middle of the cup and the straps are in the center of your shoulder. The band of the bra should feel comfortable. If it doesn't, check the fit and size of the bra against your measurements.